Paul DeLeeuw completed his high school at Cheshire Academy, followed by his graduation from Trinity College, Hartford. He then built a side career as an electronics technician. Thereafter, Paul DeLeeuw worked in his father’s hardware store for some time, but always remained doubtful of his future career path. Paul DeLeeuw also had an inclination towards defence services, when his mother pushed him to pursue medicine instead. Thereafter, he attended the Medical School of Guadalajara only to realise that this was not the place for him. Paul DeLeeuw finally received his medical degree from the University of Connecticut School of Medicine. Thereafter, he did his internship at Long Island Jewish Hospital for a year before joining the University of Missouri-Columbia as a Resident Doctor.